ORCID:

h-Index
h-Index: 84; 30132 total citations (April 2025, Web of Science)
h-Index: 102; 46392 total citations (April 2025, GoogleScholar, update here)
Selected Recent Publications
Buller, R., Lutz, S., Kazlauskas, R.J., Snajdrova, R., Moore, J.C., Bornscheuer, U.T. (2023), From nature to industry: harnessing enzymes for biocatalytic processes, Science, 382, eadh8615, link | |||
Ao, Y.F., Pei, S., Xiang, C., Menke, M.J., Shen, L., Sun, C., Dörr, M., Born, S., Höhne, M., Bornscheuer, U.T. (2023), Structure- and data-driven protein engineering of transaminases for improving activity and stereoselectivity, Angew. Chem. Int. Ed., 62, e202301660, link; Struktur- und Daten-basiertes Protein Engineering von Transaminasen zur Verbesserung von Aktivität und Stereoselektivität, Angew. Chem.135, e202301660, link. | |||
Branson, Y., Söltl, S., Buchmann, C., Wei, R., Schaffert, L., Badenhorst, C.P.S., Reisky, L., Jäger, G., Bornscheuer, U.T. (2023), Urethanases for the enzymatic hydrolysis of low molecular weight carbamates and the recycling of polyurethanes, Angew. Chem. Int. Ed., 62, e202216220, link; Urethanasen für die enzymatische Hydrolyse niedermolekularer Carbamate und das Recycling von Polyurethanen, Angew. Chem., 135, e202216220, link. | |||
Wu, S. Xiang, C., Zhou, Y., Khan, M.S.H., Liu, W., Feiler, C.G., Wei, R., Weber, G., Höhne, M., Bornscheuer, U.T. (2022), A growth selection for the directed evolution of amine-forming or converting enzymes, Nature Commun., 13, 7458, link. | |||
Müller, H., Godehard, S.P., Palm, G.J., Berndt, L., Badenhorst, C.P.S., Becker, A.K., Lammers, M., Bornscheuer, U.T. (2021), Discovery and design of family VIII carboxylesterases as highly efficient acyltransferases, Angew. Chem. Int. Ed., 60, 2013-2017, link; Entdeckung und Design promiskuitiver Acyltransferase-Aktivität in Carboxylesterasen der Familie VIII, Angew. Chem., 133, 2041-2045, link. | |||
Tang, Q., Grathwol, C.W., Aslan-Üzel, A.S., Wu, S., Link, A., Pavlidis, I.V., Badenhorst, C.P.S., Bornscheuer, U.T., (2021), Directed evolution of a halide methyltransferase enables biocatalytic synthesis of diverse SAM analogues, Angew. Chem. Int. Ed., 60, 1524-1527, link; Die gerichtete Evolution einer Halogenid-Methyltransferase erlaubt die biokatalytische Synthese diverser SAM-Analoga, Angew. Chem., 133, 1547-1551, link. | |||
Wu, S., Snajdrova, R., Moore, J., Baldenius, K., Bornscheuer, U.T. (2021), Biocatalysis: Enzymatic synthesis for industrial applications, Angew. Chem. Int. Ed., 60, 88-119, link; Biokatalyse: Enzymatische Synthese für industrielle Anwendungen, Angew. Chem., 113, 89-123, link | |||
Yi., D., Bayer, T., Badenhorst, C.P.S., Wu, S., Dörr, M., Höhne, M., Bornscheuer, U.T. (2021), Recent trends in biocatalysis, Chem. Soc. Rev., 50, 8003-8049, link. | |||
Wei, R., Tiso, T., Bertling, J., O’Connor, K., Blank, L.M., Bornscheuer, U.T. (2020), Possibilities and limitations of biotechnological plastic degradation and recycling, Nature Catal., link; see also "Behind the paper": link. | |||
Müller, H., Becker, A.K, Palm, G.J., Berndt, L., Badenhorst, C.P.S., Godehard, S.P., Reisky, L., Lammers, M., Bornscheuer, U.T. (2020), Sequence-based prediction of promiscuous acyltransferase activity in hydrolases, Angew. Chem. Int. Ed., 59, 11607-11612 link; Angew. Chem., 132, 11704-11709, link. | |||
Reisky, L., Préchoux, A., Zühlke, A.K., Bäumgen, M., Robb, C.S., Gerlach, N., Roret, T., Stanetty, C., Larocque, R., Michel, G., Song, T., Markert, S., Unfried, F., Mihovilovic, M.D., Trautwein-Schulz, A., Becher, D., Schweder, T., Bornscheuer, U.T., Hehemann, J.H. (2019), A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan, Nat. Chem. Biol., 15, 803-812, link | |||
Palm, G.J., Reisky, L., Böttcher, D., Müller, H., Michels, E., Walczak, M. C., Berndt, L., Weiss, M.S., Bornscheuer, U.T., Weber, G. (2019), Structure of the plastic-degrading I. sakaiensis MHETase bound to a substrate, Nat. Commun., 10, 1717, link. | |||
Reisky, L., Büchsenschütz, H.C., Engel, J., Song, T., Schweder, T., Hehemann, J.H., Bornscheuer, U.T. (2018), Oxidative demethylation of algal carbohydrates by cytochrome P450 monooxygenases, Nature Chem. Biol., 14, 342–344, link. | |||
Rudroff, F., Mihovilovic, M.D., Gröger, H., Snajdrova, R., Iding, H., Bornscheuer, U.T. (2018), Opportunities and challenges for combining chemo- and biocatalysis, Nature Catal. , 1, 12-22, link. | |||
Pavlidis, I.V., et al. (2016), Identification of (S )-selective transaminases for the asymmetric synthesis of bulky chiral amines, Nature Chem., 8, 1076-1082, link. | |||
Bornscheuer, U.T. (2016), Feeding on plastic, Science, 351, 1154-1155, link; see also original research paper by Yoshida et al., link. | |||
Schmidt, S., Scherkus, C., Muschiol, J., Menyes, U., Winkler, T., Hummel, W., Gröger, H., Liese, A., Herz, H.G., Bornscheuer, U.T. (2015), An enzyme cascade synthesis of ε-caprolactone and its oligomers, Angew. Chem. Int. Ed., 54, 2784-2787, link; Eine Enzymkaskade zur Synthese von ε-Caprolacton und dessen Oligomeren, Angew. Chem., 127, 2825-2828, link. | |||
Bornscheuer, U.T. et al. (2012) Engineering the third wave in biocatalysis, Nature, 485, 185-194, link. | |||
Höhne, M. et al. (2010) Rational assignment of key motifs for function guide in silico enzyme identification, Nature Chem. Biol.6, 807-813, link (Highlighted recently "Best design concept" by Nature Chem. Biol.) | |||
Kazlauskas, R.J., Bornscheuer U.T. (2009), Finding better protein engineering strategies, Nat. Chem. Biol., 5, 526-529, link. |